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Astrocytes, despite their limited phagocytic capacity compared to microglial cells, contribute by secreting several cytokines (e.g., IL-33, TGF-β, and CXCL10) that modulate strongly microglial pruning activity [173]
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This is corroborated by evidence indicating that corticosteroids may exert harmful effects on tendon architecture and regenerative capacity, particularly with repeated administration [30]
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