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In urothelial cell carcinoma (UCC) xenograft models, ADCs incorporating this inhibitor demonstrated excellent antitumor efficacy, achieving complete tumor eradication and outperforming ado-trastuzumab emtansine (Kadcyla) in therapeutic effect
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Severe isoniazid hepatotoxicity has been found in children treated concurrently with isoniazid and carbamazepine [235]
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