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A Phase IIb trial explored the efficacy of different ratios of bupropion and zonisamide in the combination, and all combinations elicited significantly more weight loss than placebo, with bupropion (360 mg) + zonisamide (360 mg) having the greatest efficacy (8.6% weight loss vs
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![In vivo detection of γ-glutamyl-transferase up-regulation in glioma using hyperpolarized γ-glutamyl-[1-13C]glycine](https://media.springernature.com/m685/springer-static/image/art%3A10.1038%2Fs41598-020-63160-y/MediaObjects/41598_2020_63160_Fig1_HTML.png)
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