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Barrier pathophysiology in development 3.1 Pediatrics The intestine at birth is not fully developed and many factors, such as diet, stress and microbiota have been implicated in influencing its permeability during development [50][51][52]
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Predrag Sikiric and colleagues first characterized this peptide in the late 1990s, identifying it as a stable fragment of a larger protein found in human gastric juice
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