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For example, prostacyclin (PGI2) is a potent vasodilator that helps maintain normal blood pressure, while thromboxane A2 (TXA2) is a vasoconstrictor and promotes platelet aggregation, increasing the risk of thrombosis

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When Tesamorelin binds with the GHRH receptor in the pituitary glands, it stimulates the release of the growth hormone that sends signals to the liver to produce insulin-like growth factor-1 (IGF-1)