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Patients with pre-existing diabetic retinopathy — a class caution exists (based on semaglutide data) that rapid improvement in glycaemic control may be associated with early worsening of diabetic retinopathy
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While TB-500 exhibits similar pro-angiogenic behavior, it lacks certain regions—such as the Ac-SDKP motif—believed to mediate cytoprotective effects during acute ischemic stress
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