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Previous research has demonstrated that supplementing probiotics helps maintain the balance of gut microbiota in the host, while also increasing the number of beneficial bacteria and reducing the colonization of harmful bacteria in the intestinal tract ( Bacillus velezensis isolated from Tibetan yaks can enhance the gut microbiota of mice ( Bacillus velezensis TS5 decreased the relative abundance of potential harmful bacteria such as Helicobacter , Unspecified_Desulfovibrionaceae , and Colidextribacter in the cecum and improved the composition of the mice’s cecum microbiota to a certain extent