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These notably include mixed GS-S-protein disulfides, GS conjugates with electrophilic metabolites, and GSNO (Fig
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Potency:50 mg
As the disease advances, the progressive loss of mDAergic input to the striatum results in decreased motor function with symptoms that include bradykinesia, rigidity, tremor, and postural instability, although the underlying mechanisms leading to these symptoms are incompletely understood [1,2]
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