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When a pathogen invades, TNF receptor-associated factor 3 (TRAF3) ubiquitinates TBK1 to activate it, and activated TBK1 phosphorylates interferon regulatory factor 3 (IRF3) to induce type I interferon expression or sequestosome-1 (p62) to induce autophagy [27, 28]

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The judge’s ruling is crucial to the future of the Tylenol pregnancy lawsuit