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officinale could inhibit inflammatory mediators of COX-2 with IC 50 values of 32, 7.5, and 17.5 μM, respectively, but there is no inhibitory activity reported in COX-1
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The researchers pored over more than 10 years of data for patients 65 and older from the Veterans Affairs Administration comparing the records for 46,000 patients who got one antipsychotic drug or antidepressant for symptoms of dementia with an roughly equal number of patients in similar circumstances who didn't receive an antipsychotic drug
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