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A substantial body of peer-reviewed research, largely conducted in rodent models, has investigated BPC-157's interactions with the nitric oxide (NO) system, growth hormone receptors, and vascular endothelial growth factor (VEGF) pathways

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Hepcidin expression involves several proteins present on the plasma membrane of hepatocytes, which constitute the iron-sensing complex: human hemochromatosis protein (HFE), transferrin receptor 2 (TfR2), hemojuvelin (HJV) and bone morphogenetic protein-6 (BMP-6) [23]