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Importantly, the anti-tumor protection conferred by early ferroptotic cells depended on ATP-Purinergic Receptor P2X7 signaling, as blockade with oxidized-ATP abolished this effect, highlighting how DCs process and present tumor antigens via MHC complexes to activate T cells (41)
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8 iFSP1 sensitizes cancer cell lines from different origins to RSL3-induced ferroptosis
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