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The question of whether GLP-1 therapy qualifies as direct immunomodulation or whether the benefits are primarily mediated through weight loss and reduced adipose inflammation is still under active investigation
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As the main site of drug metabolism, the liver plays an important role in detoxifying and facilitating the excretion of xenobiotics, such as the enzymatic conversion of lipid‐soluble compounds to more water‐soluble components [62]
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