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What B12 Deficiency Can Look Like (Spoiler: Everything) For me — and for thousands of others — it looked like: Widespread nerve pain Brain fog and memory problems Chronic fatigue and weakness Depression and anxiety Shortness of breath and dizziness Digestive issues like IBS Unexplained weight changes Vision disturbances Balance and coordination trouble Burning tongue or mouth Suspected autoimmune diseases like MS or lupus Over time, untreated B12 deficiency can cause irreversible neurological damage , dementia-like symptoms, and even death