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The most common adverse reaction to allopurinol is an increase in gout attacks early in therapy
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[ 192 ] Another report has shown that inhibition of BACH1 in C2C12 myoblast cells leads to decreased cell proliferation, formation of myotubes, and expression of myogenin potentially by the up‐regulation of SMAD2, SMAD3, and FOXO1, which suppresses the differentiation of muscle cells
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