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Placental Origins of Preeclampsia: Potential Therapeutic Targets

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Therefore, the commensal microbiota is often regarded as “a hidden organ.” Commensal microbiota-derived metabolites have substantial impacts on host physiological functions through metabolic reprograming (64), epigenetic modifications (65), and the activation of specific receptors like G protein-coupled receptors (GPRs) and aryl hydrocarbon receptor (AhR)