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Analysis of targets related to Alzheimer’s disease pathology Alzdata (Xu et al., 2018) consisted of high-throughput omic data (e.g., Genomics, Transcriptomes, Proteomics, and Functional genomics), and high-confident functional data (e.g., neuroimaging screening, population-based longitudinal studies, and transgenic mouse phenotyping)

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Concurrently, the emergence of “molecularly intelligent” photosensitizers that change their photophysical or chemical behavior in response to lesion-specific cues (pH, enzymes, redox) exemplifies how analyte-sensing functionality can be built directly into imaging-therapeutic agents