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Once bound to glucocorticoids, a conformational change and phosphorylation by MAP kinase induce translocation of the GR to the nucleus, where GR binds to glucocorticoid response elements (GRE) in the promoter region of target genes [38]

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Analogous findings were observed in the case of infection with the tick-borne spirochete Borrelia burgdorferi [138]

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