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A 2021 analysis of the VITamin D and OmegA-3 TriaL (VITAL) showed that omega-3 supplementation did not affect migraine frequency or severity among the 1,032 study participants with a reported a history of probable migraine

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Together, this pairing has been suggested to engage distinct but complementary mechanisms, potentially influencing how growth hormone-related signals are processed in the pituitary and hypothalamus