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Within the small intestine, citrulline is synthesized from glutamine by the enterocytes, releasing citrulline into blood circulation for metabolism into arginine by the kidneys [36]

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The Role of LRG1 in Abnormal Angiogenesis of DN The Biological Characteristics of LRG1 LRG1 is a highly conservative member of leucine-rich repeat family that firstly identified in human serum in 1977 (Haupt and Baudner, 1977)