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The addition of high dose niacin was intended to increase HDL ("good") cholesterol, reduce elevated triglycerides, and, most importantly, reduce the risk of heart attacks and stoke

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The analysis was based on the expression of 98 cell cycle genes corresponding to cell cycle phases: S phase of DNA synthesis (43 genes), G2/M phase of checkpoint and cell division (combined G2 and M phases, 55 genes) and G1 phase of cell growth (cells expressing none of the 98 cell cycle genes)