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Moreover, H 3 receptors are upregulated in the prefrontal cortex of people with schizophrenia (Jin et al., 2009a), with initial animal studies demonstrating that H 3 receptor antagonists improved symptoms of cognitive impairment (Southam et al., 2009

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These nanomedicines are small spherical particles of nanometric size (generally between 100 and 200 nm) that can carry a whole range of molecules