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Why you can't live without glutathione | IMI Hong Kong

Nat Rev Dis Primers 5 , 69 (2019)

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Using primary cultured dopaminergic cells harvested from the SN of MPTP resistant Swiss-Webster mice [171], inhibition of GST by ethacrynic acid or siRNA directed against GSTpi increases the amount of MPP + -induced DA neuron death to levels that mimic neurons from an MPTP-sensitive C57BL/6 strain