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Thymosin Alpha-1 (thymalfasin) may be available through FDA-registered compounding pharmacies under specific physician supervision

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The current standard operating procedure by the European Center for the Validation of Alternative Methods (ECVAM) recommends the use of MTT reduction as parameter to make prediction on the skin irritancy of substances using EpiSkin TM test method, while IL-1α endpoint is regarded as a useful adjunct to MTT assay 48