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Oxidative stress plays a critical role in its pathogenesis, as ROS and RNS produced during inflammation stimulate melanocyte proliferation and melanin synthesis, primarily via upregulation of TYR activity 130

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Seek emergency medical attention immediately if you experience more severe symptoms, such as difficulty breathing, dizziness, or swelling of the face or throat, as these could be signs of a serious allergic reaction (anaphylaxis)