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Work from David Savage’s group showed that PLIN1 mutations from patients with lipodystrophies, which lack the C-terminus, fail to stabilize ABHD5 on LDs, resulting in greater basal lipolysis (137) and likely explains why these patients are unable to sequester FAs into TAGs

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Using a lesser diluent, like simple sterile water, is possible for single-use applications, but it offers no protection against contamination once the vial's septum has been punctured