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In SLE patients, Treg cell dysfunction has been found to result from a persistent decrease in Foxp3 expression in Tregs, mediated by the involvement of the OX40L/OX40 axis (163)

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(c) Example scatterplots demonstrating the lack of correlation between input DNA amounts ( x axis) according to own measurements (top) and consensus concentration (bottom) on the one hand, and the assay performance on the other hand ( y axis)