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Additionally, the MST1–BUB3 interaction triggers the upregulation of the Akt–mTORC1 pathway (involving the serine‐threonine kinase Akt and rapamycin complex 1), which promotes cell proliferation and survival [351]

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Impaired mitochondrial biogenesis contributes to depletion of functional mitochondria in chronic MPP+ toxicity: dual roles for ERK1/2