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In preclinical studies, β‐carotene tended to maintain myocardial GSH levels and GPX activities and reduce oxidative stress in vitro and in vivo [143, 144]

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Macrophages In murine peritoneal macrophages RSL3 blocks pro-inflammatory responses upon lipopolysaccharide treatment by inducing NRF2, which inhibits the recruitment of RNA polymerase II to the transcription start site of several cytokines [330]