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Si Miao San attenuates inflammation and oxidative stress in rats with CIA via the modulation of the Nrf2/ARE/PTEN pathway

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Arsenic induced the expression of COX-2, VEGF, HIF-1, and interleukin- 6 (IL-6), which were regulated by ERK, JNK, and p38 MAPK in simian virus-40 (SV-40) immortalized human uroepithelial cells and mouse lymphatic endothelial cells, mediated by ROS [75,86,88]

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