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Nevertheless, glucocorticoid-induced new spines then tend to stabilize and survive long term, which requires longer-lasting, transcriptional mechanisms that largely remain to be determined (Leslie and Nedivi, 2011)
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178,179,180,181,182 Given that DNA damage-activated PARPs account for up to 90% of cellular NAD + consumption, the DNA repair activity is highly dependent on the cellular NAD + concentration
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