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Under conditions of high iron load and chronic inflammation—particularly in late-stage triggering receptor expressed on myeloid cells 2 (TREM2^low) foam macrophages, which are more prone to ferroptosis—overexpression of HO-1 can lead to mitochondrial dysfunction, increasing cellular vulnerability to oxidative damage (cell viability reduced by approximately 30%) (14)
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Potency:50 mg Orange
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