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Boosting NAD+ blunts TLR4-induced type I IFN in control and systemic lupus… [PMID: 35025762] Laboratory literature summary: Boosting NAD+ blunts TLR4-induced type I IFN in control and systemic lupus erythematosus monocytes

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Abstract The STEP 5 trial assessed the efficacy and safety of once-weekly subcutaneous semaglutide 2.4 mg versus placebo (both plus behavioral intervention) for long-term treatment of adults with obesity, or overweight with at least one weight-related comorbidity, without diabetes