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B12 injections are most clearly indicated when: A person has confirmed B12 deficiency that requires rapid replacement There’s a known or likely absorption issue There’s a need for ongoing maintenance due to non-dietary causes (for example, autoimmune gastritis) Typical treatment schedules (UK guidance) Treatment schedules can vary depending on symptoms, severity, and cause
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Later research found that more of it is excreted in urine compared with methylcobalamin which suggests that less is retained by the body
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