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Poster Session I - INTRACRANIAL HEMORRHAGE 02.00 - INTRACRANIAL HEMORRHAGE - 02.01 - INTRACEREBRAL HAEMORRHAGE P155 - ESOC25-1333 MOLECULAR BIOMARKERS IN CEREBRAL AMYLOID ANGIOPATHY WITH AND WITHOUT SYMPTOMATIC INTRACEREBRAL HAEMORRHAGE Benedetta Storti *1 , Alessandro Francia 1,2 , Giulia Marinoni 1 , Benedetta Cefaloni 3 , Nicola Rifino 1 , Giorgio Boncoraglio 1 , Antonio Indaco 4 , Giuseppe Di Fede 4 , Mario Stanziano 5 , Isabella Canavero 1 , Anna Bersano 1 1 Cerebrovascular Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy, 2 Department of Biomedical and Clinical Sciences, University of Milan, Milan, Italy, 3 Dipartimento di Matematica, Politecnico di Milano, Milan, Italy, 4 Neuropathology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy, 5 Neuroradiology Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy Background and Aims: Cerebral amyloid angiopathy (CAA) typically presents as lobar intracerebral haemorrhage (ICH) or cognitive impairment

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Importantly, B 12 supplementation generally relieved the upregulation of these genes, in support of the idea that limiting B 12 levels were driving the Met restriction in vivo

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