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In these cases, treatment should be initiated as soon as possible.[] The etiology of vitamin B12 deficiency typically includes malabsorption-related causes such as autoimmune gastritis (pernicious anemia), celiac disease, inflammatory bowel disease, surgical gastrectomy, gastric bypass, and ileal resection
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Although ADCP-induced phagocytosis is related to CD38 level on targeted cells, differences in CD38 expression levels of different target cell lines do not appear to be a convincible explanation for the differences in phagocytosis-mediated elimination [73]
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