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It is important to mention that these O 2 levels do not represent the concentrations found inside human healthy and cancerous tissues and are followingly used to investigate the different therapeutic efficiency of the nanoparticle formulation in high and low O 2 atmospheres

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Glutathione Redox Balance in Health The redox state of GSH and GSSG in healthy individuals has been well described (154, 156, 157, 231, 288)