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3.1 Signaling modulation for hepatic differentiation By mimicking the development signaling, stepwise chemical treatment induces differentiation of human embryonic stem cells (hESCs), induced PSCs (iPSCs), and human PSCs into hepatocytes
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Program:8 Week Skin and Tissue Optimization
Markers of AKI in the Pediatric Population The diagnosis of AKI, per the Kidney Disease Improving Global Outcomes (KDIGO) guidelines, is currently defined by factors including elevated serum creatinine concentration, decreased UO, and renal replacement therapy requirement ( NGAL is a protease-resistant polypeptide of the lipocalin superfamily identified in human neutrophils and is expressed by the tubular epithelia of the kidneys in response to inflammation ( KIM-1, a type-1 transmembrane protein expressed in the renal proximal tubular cells, is significantly upregulated following ischemia ( IL-18 is a cytokine in the IL-1 superfamily that is synthesized by monocytes, macrophages, and proximal tubular epithelial cells of the kidney