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Of note, Caco-2 cells at day 2 appeared to be relatively resistant to RSL3-driven ferroptosis when compared to other colorectal cancer cell lines ( FIGURE 1 3.2 Differentiating Caco-2 cells develop increased resistance to CLnA-induced ferroptosis Caco-2 cells were cultured over 21 days in order to differentiate into enterocytes and were exposed to different fatty acids with various degrees of unsaturation and chain lengths every second or third day
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