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Declarations Authors’ contributions Designed the paper, selected and prepared the references, prepared the figures, wrote the manuscript: Wright JW Prepared the references, wrote the manuscript: Harding JW Availability of data and materials Not applicable

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for example, Myc, increases gene expression of the glutamine transporters (ASCT2 and SN2) and glutaminase 1, which together augments glutamine consumption, thus supplying 2-oxo to KC (11, 12)