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Participants were randomized in a double-blind placebo-controlled fashion into 2 groups: Methylsulfonylmethane (MSM) (n = 8) and placebo (n = 8)

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Mechanisms include: UVB: Direct DNA damage (CPDs) that impair fibroblast function UVA: Oxidative stress that degrades collagen and elastin Anatomical reflection: Light bounces into the orbital area, increasing cumulative exposure This is why we stress sunscreen around the eye area is not optional