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Structural activation mechanism of cagrilintide bound to amylin and calcitonin receptors

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In addition, other regulatory pathways and regulatory factors, such as the NADPH-FSP1-CoQ10 regulatory pathway, GCH-1-BH4 regulatory pathway, protein posttranslational modification mechanism, and mitochondrial ferroptosis defense mechanism mediated by dihydro whey acid dehydrogenase (DHODH), have been identified as key factors in ferroptosis (39–49) ( Figure 1 )