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And, when the V max values are set to 10% of their normal values, the number of functional hepatocytes decreases to 10% of normal after 40 hours (the red curve), well below the grey bar marking 30% remaining hepatocytes, which is thought to be the threshold for liver failure [10]

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In ALS, iron accumulation has been reported in the deep cortical layers as well as in microglia in the motor cortex 6